Practicing Medical Skills in a Small Clinic

Chapter 860 - 405: A Mature Doctor Considers All Factors, Superwarfarin Poisoning? (Part 3)

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Chapter 860: Chapter 405: A Mature Doctor Considers All Factors, Superwarfarin Poisoning? (Part 3)

When Li Jingsheng examined the patient’s body, he discovered large subcutaneous bruises on the inner thigh.

Is there widespread subcutaneous bleeding?

"Lupus!"

A disease suddenly popped into Li Jingsheng’s mind.

Lupus manifests in various ways and can also cause coagulation disorders.

However, after examination, he ultimately ruled out lupus.

The patient didn’t have any rashes or noticeable blisters in the oral mucosa, or other abnormalities like damage.

The diagnosis was once again at a standstill.

"Did you do blood tests at Qiaobang Hospital?"

Li Jingsheng asked the family member.

"Yes, the results were similar to those from the county hospital. Later, the doctor also screened blood and urine for toxins, and they said it was negative."

The woman logged into the Qiaobang Hospital app and then showed the test results to Li Jingsheng.

"Does your dad live alone usually?"

"Yes! My brother and I have both bought houses in the city and settled down. We wanted to bring him to live in the city, but he always says he’s not used to it. We had no choice but to let him be. He usually stays at home alone, farming over a dozen acres of land, raising a few pigs, two cows, chickens, and laying eggs, which he never eats himself. He always saves them for my brother and me..."

As she spoke, the woman’s eyes turned red.

She took out a tissue to wipe her tears.

The affection between family members is indeed hard to let go of.

Especially when facing life and death, family ties feel even more precious.

"Uncle, can you talk to me?"

Li Jingsheng looked at the patient, seeing the old man’s gaze was slightly vacant, but he likely had the ability to think.

He should be conscious.

"Yes!" The patient nodded.

He seemed to have some difficulty speaking.

"Do you usually have symptoms of chronic diarrhea?"

"Huh?"

The patient didn’t quite understand.

The woman repeated it to the old man in dialect, and only then did he understand.

"No."

While speaking, the old man’s head kept trembling and shaking.

Li Jingsheng looked at the woman, "Did you tell the doctor at Qiaobang Hospital your dad’s specific symptoms?"

"Of course, we did!"

"Can you show me all the test results from over there? My small clinic has limited resources, and many tests can’t be done."

Li Jingsheng explained.

Qiaobang Hospital might perform that experiment with the correction using normal plasma.

Sure enough, he quickly saw this test.

The results were already out.

Multiple coagulation factors were abnormal, with deficiencies in FII, FVII, FIX, while some coagulation factors were entirely normal.

After seeing these results, Li Jingsheng was slightly surprised.

It indicated that the patient had a vitamin K-dependent coagulation factor deficiency.

How could a normal person suddenly have vitamin K deficiency?

The role of vitamin K is to allow proteins dependent on it, including FII, FVII, VIX, and FX, as well as protein S, and protein C to be carboxylated into γ-carboxyglutamic acid in the activation site through carboxylases.

Then it binds with calcium ions to activate.

Now it’s basically confirmed that the abnormal coagulation factors are due to vitamin K deficiency.

This should be the culprit causing the patient’s bloody stool, hematuria, and other issues.

In clinical practice, when vitamin K deficiency is mentioned, almost any doctor with a bit of experience would think of a certain drug.

Its name is Warfarin.

This poison was developed by humans to deal with rats.

After rats consume it, it results in coagulation disorder and ultimately death.

Its toxicity to humans, poultry, and livestock also exists.

Could the patient have accidentally ingested Warfarin?

However, the toxic screening of blood and urine was entirely negative.

This plunged Li Jingsheng’s diagnosis into difficulty once again.

Vitamin K can be provided by some foods and is a fat-soluble vitamin.

In addition to food provision, a portion is synthesized by intestinal cells and then absorbed by the small intestine.

If the patient is not suffering from warfarin poisoning, could there be an absorption issue with the small intestine?

Could the small intestine not absorb the vitamin K synthesized by intestinal cells?

This possibility exists.

"Does your dad have diarrhea symptoms now?"

Li Jingsheng, facing the disease, remained resilient, constantly striving to investigate every possible suspected cause.

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